免疫学/炎症学

食物アレルギー、小児

Crestani E, Benamar M, Phipatanakul W, et al. Age-specific Metabolomic profiles in children with food allergy. (2024) Clinical Immunology,

DOI: 10.1016/j.clim.2024.109928.

口腔、炎症、バイオマーカー

Virdee SS, Bashir N, Krstic M, et al. Periradicular tissue fluid-derived biomarkers for apical periodontitis: an in vitro methodological and in vivo cross-sectional study. (2023) International Endodontic Journal,

DOI: 10.1111/iej.13956

食道、炎症

Kleuskens MTA, Bek MK, Al Halabi Y, et al. Mast cells disrupt the function of the esophageal epithelial barrier. (2023) Mucosal immunology,

DOI: 10.1016/j.mucimm.2023.06.001

腸管、遺伝子変異

Rodari MM, Cazals-Hatem D, Uzzan M, et al. Insights into the expanding intestinal phenotypic spectrum of SOCS1 haploinsufficiency and therapeutic options. (2023) Journal of Clinical Immunology,

DOI: 10.1007/s10875-023-01495-7

喘息、感染

Radzikowska U, Eljaszewicz A, Tan G, et al. Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19. (2023) Nature Communications,

DOI: 10.1038/s41467-023-37470-4

COVID-19、mRNAワクチン、心血管疾患

Ong EZ, Koh CWT, Tng DJH, et al. RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication. (2023) Med,

DOI: 10.1016/j.medj.2023.04.001

薬理学、グルココルチコイド

Othonos N, Pofi R, Arvaniti A, et al. 11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial. (2023) Nature Communications,

DOI: 10.1038/s41467-023-36541-w

症例報告、遺伝子変異、小児

Michniacki TF, Walkovich K, DeMeyer L, et al. SOCS1 Haploinsufficiency Presenting as Severe Enthesitis, Bone Marrow Hypocellularity, and Refractory Thrombocytopenia in a Pediatric Patient with Subsequent Response to JAK Inhibition. (2022) Journal of Clinical Immunology,

DOI: 10.1007/s10875-022-01346-x.

神経学

スポーツ関連脳震盪、免疫

Di Battista AP, Rhind SG, Shiu M, et al. Whole blood stimulation provides preliminary evidence of altered immune function following SRC. (2024) BMC Immunology,

DOI: 10.1186/s12865-023-00595-8

アルツハイマー、臨床試験

Faridar A, Eid AM, Thome AD, et al. A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease. (2023) Translational Neurodegeneration,
DOI: 10.1186/s40035-023-00387-5

多発性硬化症、免疫吸着療法

Pfeuffer S, Rolfes L, Wirth T,  et al. Immunoadsorption versus double-dose methylprednisolone in refractory multiple sclerosis relapses. (2022) Journal of Neuroinflammation,
DOI: 10.1186/s12974-022-02583-y

筋萎縮性側索硬化症、制御性 T リンパ球

Thonhoff JR, Berry JD, Macklin EA, et al. Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis. (2022) Neurology, Neuroimmunology and Neuroinflammation,
DOI: 10.1212/NXI.0000000000200019

老化

術後せん妄、老化、バイオマーカー

Lozano-Vicario L, Muñoz-Vázquez ÁJ, Ramírez-Vélez R, et al. Association of postoperative delirium with serum and cerebrospinal fluid proteomic profiles: a prospective cohort study in older hip fracture patients. (2024) GeroScience,
DOI: 10.1007/s11357-024-01071-w

高齢者、骨粗鬆症、骨折、バイオマーカー

Cedeno-Veloz BA, Lozano-Vicario L, Zambom-Ferraresi F, et al. Effect of immunology biomarkers associated with hip fracture and fracture risk in older adults. (2023) Immunity & Ageing,
DOI: 10.1186/s12979-023-00379-z

高齢者、骨折、バイオマーカー

Cedeno-Veloz B, Lozano-Vicario L, Rodríguez-García A, et al. Serum biomarkers related to frailty predict negative outcomes in older adults with hip fracture. (2023) Journal of Endocrinological Investigation,
DOI: 10.1007/s40618-023-02181-6

栄養学

栄養、免疫

Kawano T, Miura A, Naito J, et al. High-parameter immune profiling and subjective health assessment of the immunomodulatory effects of paramylon-rich Euglena gracilis EOD-1: A randomized, double-blind, placebo-controlled, parallel-group study. (2023) Journal of Functional Foods,

DOI: 10.1016/j.jff.2023.105804

感染症（COVID-19）

COVID-19後遺症、マルチオミクス

Mahdi A, Zhao A, Fredengren E, et al. Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 syndrome with and without postural orthostatic tachycardia syndrome: a multi-omic profiling study. (2023) Scientific Reports,
DOI: 10.1038/s41598-023-47539-1

COVID-19後遺症、炎症

Allan-Blitz LT, Goodrich J, Hu H, et al. Altered Tumor Necrosis Factor Response in Neurologic Postacute SARS-CoV-2 Syndrome. (2023) Journal of Interferon & Cytokine Research,
DOI: 10.1089/jir.2023.0051

COVID-19、バイオマーカー

Rosendal E, Mihai IS, Becker M, et al. Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections. (2022) mBio,
DOI: 10.1128/mbio.00892-22